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No actual storyline has ever been revealed for this movie, but here's what I came up with:

Stab 4: Knife of Doom takes us back before Hollywood, before Windsor College, before Woodsboro, to a small town in New Hampshire where 21-year-old Gale Weathers (Jessica Alba) is reporting for her college newspaper. When her best friend is brutally slain, Gale sets out to find the killer known as Ghost Face, a local urban legend with roots back to the 1800’s.  Can Gale solve the case before all of her friends are gruesomely murdered or will she land on the chopping block with them? 

Based on the book by Woodsboro survivor Gale Weathers and featuring a brand-new cast of fresh faces, Stab 4: Knife of Doom gives new life to the franchise... before Ghostface takes it away!

FUN FACT #1 This film was based on the Gale Weather's book "Knife of Doom."

FUN FACT #2 The subtitle "Knife of Doom" was never shown in the Scream movies on posters, DVD cases or on screen. It was added on the fan created DVD covers. So, it may not actually be part of the title of the film.

FUN FACT #3 In Scream 4, it was stated that Sidney threated to sue the studio if they used her story after Stab 3, so it's safe to assume that the Sidney character wasn't used again. However, in Scream 5, the killer says “Sidney was in all the Stab movies, except the last one.” So, who's right? We don't know and apparently neither do the writers of the Scream movies.